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Updated: Apr 6, 2026

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
Published on: October 29, 2021
ASSESSMENT OF QUALITY OF LIFE IN PATIENTS AFTER LOWER LIMB AMPUTATION.
Lower extremity amputation significantly impacts quality of life, with amputees scoring lower on health surveys. Lower amputation levels correlate with better physical functioning, irrespective of gender.
Area of Science:
- Rehabilitation Medicine
- Health Outcomes Research
- Amputee Care
Background:
- Lower extremity amputation presents significant anatomical, functional, psychological, and social challenges impacting patient quality of life.
- Understanding these impacts is crucial for developing effective rehabilitation strategies.
Purpose of the Study:
- To compare the quality of life between individuals with lower extremity amputation and those without.
- To investigate the influence of gender and amputation level on quality of life outcomes.
Main Methods:
- A cross-sectional study involving 56 participants (28 with lower extremity amputation, 28 controls).
- The Research ANd Development (RAND) 36-Item Health Survey 1.0 (SF-36) was utilized to assess quality of life.
- Participants were categorized by amputation level (transfemoral vs. transtibial).
Main Results:
- Patients with lower extremity amputation reported significantly lower quality of life across all SF-36 variables compared to the control group (p<0.05).
- No significant gender-based differences were observed in SF-36 scores.
- Individuals with transtibial amputations demonstrated higher scores in physical functioning and general health status compared to those with transfemoral amputations (p<0.05).
Conclusions:
- Lower extremity amputation leads to substantial quality of life limitations, independent of gender.
- Transtibial amputations are associated with better physical functioning outcomes compared to transfemoral amputations.
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