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Updated: Jul 15, 2026

Chromatographic Fingerprinting by Template Matching for Data Collected by Comprehensive Two-Dimensional Gas Chromatography
Published on: September 2, 2020
One-dimensional and comprehensive two-dimensional gas chromatography coupled to soft photo ionization time-of-flight
W Welthagen1, S Mitschke, F Mühlberger
1Analytical Chemistry, Institute of Physics, University of Augsburg, D-86159 Augsburg, Germany.
Abstract:
Soft laser photo-ionization mass spectrometry is presented as a separation dimension hyphenated with gas chromatographic techniques. Single photon ionization (SPI) is a universal soft ionization method which ionizes organic molecules with an ionization potential below 10.5 eV if 118 nm laser radiation is used. The inherently soft ionization of photo ionization techniques can further be utilized together with gas chromatography as a comprehensive two-dimensional separation method (GC x MS), using the GC retention time as first separation dimension and the molecular mass as second separation dimension. Some GC x MS chromatograms of diesel petroleum samples using SPI are presented and discussed. Finally, it is demonstrated that the coupling of soft SPI mass spectrometry with comprehensive two-dimensional gas chromatography (GC x GC) provides a three-dimensional separation technique (GC x GC x SPI-MS).
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