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Updated: Jul 15, 2026
12:53
Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
Published on: May 19, 2018
Mycotic lymphadenitis in cattle and Swine
Summary
Mycotic lymphadenitis in cattle and pigs is primarily caused by zygomycetes, often affecting mesenteric lymph nodes in cattle. Histological examination revealed characteristic granulomas with specific fungal hyphae and isolates.
Area of Science:
- Veterinary Pathology
- Mycology
- Infectious Diseases
Background:
- Mycotic infections can cause significant pathology in livestock.
- Lymphadenitis, inflammation of lymph nodes, can manifest with diverse etiologies.
- Zygomycetes are a class of fungi known to cause opportunistic infections.
Purpose of the Study:
- To characterize mycotic lymphadenitis in cattle and pigs.
- To identify the fungal agents responsible for granulomatous lesions in lymph nodes.
- To describe the histopathological features of these infections.
Main Methods:
- Examination of lymph node samples from 100 cattle and 9 pigs.
- Histopathological analysis of granulomatous lesions.
- Fungal isolation and identification, including microscopic morphology.
Main Results:
- Over 90% of bovine mycotic lymphadenitis cases occurred in mesenteric nodes; swine lesions were multifocal.
- All infections were attributed to zygomycetes, with Mucoraceous-type hyphae prevalent.
- Absidia corymbifera, Rhizopus rhizopodiformis, and R. oryzae were isolated; R. rhizopodiformis produced chlamydospores.
Conclusions:
- Zygomycetes are a significant cause of mycotic lymphadenitis in cattle and pigs.
- Distinct patterns of lymph node involvement exist between cattle and swine.
- Histopathology and fungal isolation are crucial for diagnosing these mycotic infections.
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