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Updated: Jul 15, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Anti-reflux pouch-esophagostomy after total gastrectomy
Michiya Kobayashi1, Ken Okamoto, Takehiro Okabyashi
1Department of Human Health and Medical Science, Kochi Medical School, Nankoku, Japan.
A new jejunal pouch-esophagostomy procedure with partial posterior wrapping effectively minimizes severe reflux esophagitis after total gastrectomy, improving patient outcomes.
Area of Science:
- Surgical Innovation
- Gastroenterology
- Oncology
Background:
- Severe reflux esophagitis is a significant complication following total gastrectomy.
- Current surgical techniques may not fully prevent postoperative reflux.
Purpose of the Study:
- To introduce and evaluate a novel jejunal pouch-esophagostomy procedure with partial posterior wrapping.
- To assess the efficacy of this technique in minimizing reflux esophagitis after total gastrectomy.
Main Methods:
- A 35 cm jejunal segment was folded, creating a side-to-side jejuno-jejunostomy.
- An esophago-jejuno anastomosis formed an "apical bridge" for partial posterior fundoplication-like wrapping.
- The procedure was performed as part of total gastrectomy.
Main Results:
- Barium meal testing revealed minimal postoperative reflux, even in the Trendelenburg position.
- The novel anti-reflux anastomosis procedure demonstrated significant efficacy.
Conclusions:
- Jejunal pouch reconstruction with partial posterior wrapping is a valuable addition to total gastrectomy.
- This technique effectively minimizes the risk of reflux esophagitis, enhancing patient recovery.
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