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Updated: Jul 15, 2026
07:00
Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
Published on: October 13, 2016
[Management and care for patients with ALS]
Hiroshi Mitsumoto1, Wesley J Howe
1Eleanor and Lou Gehrig MDA/ALS Research Center, Neurological Institute, Columbia University, USA.
Rinsho Shinkeigaku = Clinical Neurology
|April 17, 2007
Summary
Amyotrophic Lateral Sclerosis (ALS) research has advanced significantly with new discoveries and treatments. Multidisciplinary clinics and supportive therapies like ventilation and feeding improve patient care and quality of life.
Area of Science:
- Neurology
- Genetics
- Clinical Practice
Context:
- Recent advances in understanding Amyotrophic Lateral Sclerosis (ALS) include SOD1 mutations and transgenic models.
- The development of ALS practice guidelines and national databases reflects evolving clinical standards.
- Multidisciplinary ALS clinics are now standard of care, offering specialized support.
Purpose:
- To review the significant progress and current landscape of Amyotrophic Lateral Sclerosis (ALS) research and clinical practice.
- To highlight key developments impacting ALS patient care and future therapeutic strategies.
Summary:
- Key breakthroughs include SOD1 mutation discovery, riluzole introduction, and the establishment of multidisciplinary ALS clinics.
- Supportive care measures such as non-invasive positive pressure ventilation and enteral feeding demonstrate benefits for quality of life and survival.
- Ongoing clinical trials are exploring novel pharmacological agents for ALS treatment, indicating a dynamic research environment.
Impact:
- Improved patient outcomes and quality of life through specialized multidisciplinary care and supportive interventions.
- Accelerated drug discovery and development for ALS, driven by a deeper understanding of disease mechanisms.
- Establishment of global standards in ALS care, enhancing consistency and effectiveness of treatment approaches.
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