Related Experiment Video
Updated: Jul 15, 2026
05:06
Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
Published on: February 28, 2025
Normalization in the appearance of severly damaged psoriatic nails using soft x-rays. A case report
Jaka Rados1, Ivan Dobrić, Aida Pasić
1Department of Dermatology And Venereology, Zagreb University Hospital Center, Salata 4, HR-10000 Zagreb, Croatia. sodarakaj@yahoo.com
Acta Dermatovenerologica Croatica : ADC
|April 17, 2007
Summary
Soft x-ray radiotherapy offers a promising, long-lasting treatment for severe nail psoriasis. This approach effectively normalized nail plates in a patient with significant thickening, providing relief from functional and cosmetic issues.
Area of Science:
- Dermatology
- Oncology
Background:
- Nail psoriasis affects 10-55% of psoriasis patients and up to 85% with psoriatic arthritis.
- Despite significant patient discomfort and advances in skin psoriasis treatment, effective long-term nail psoriasis therapies are lacking.
Observation:
- A 51-year-old male patient with severe nail psoriasis and nail plate thickening (up to 30x normal) was treated.
- The patient received fractionated soft x-ray radiotherapy (total 13.5 Gy).
Findings:
- Complete normalization of nail plates was observed 12 months post-therapy.
- The patient remained relapse-free for nearly three years without radiotherapy side effects.
Implications:
- Soft x-ray radiotherapy demonstrates high efficacy and long-lasting remission for severe nail psoriasis with nail thickening.
- This treatment modality warrants consideration for alleviating the functional and psychical burdens of severe psoriatic nail disease.
