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Related Experiment Video

Updated: Jul 15, 2026

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera
09:34

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera

Published on: January 27, 2023

Clinical models that objectively evaluate interproximal plaque based on total protein concentration.

N Milanovich1, S M Souza, M de Jager

  • 1Philips Oral Healthcare, Snoqualmie, WA 98065, USA. nick.milanovich@philips.com

Journal of Clinical Periodontology
|April 25, 2007
PubMed
Summary

New clinical models accurately measure interproximal plaque (IPP) levels using total protein concentration. These models offer objective, quantitative assessments for improved oral hygiene research and development.

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Area of Science:

  • Oral Health Research
  • Biomarker Discovery
  • Clinical Trial Design

Background:

  • Accurate quantification of interproximal plaque (IPP) is crucial for evaluating oral hygiene efficacy.
  • Existing methods for IPP assessment may lack objectivity or precision.
  • Development of novel, quantitative biomarkers for plaque is needed.

Purpose of the Study:

  • To establish and validate clinical models for objective assessment of interproximal plaque (IPP) levels.
  • To utilize total protein concentration as a quantitative measure for IPP.
  • To compare the efficacy of different plaque removal strategies using these models.

Main Methods:

  • Randomized, double-blinded, crossover studies utilizing multiple treatment (MTM) and single-treatment models (STM).

Related Experiment Videos

Last Updated: Jul 15, 2026

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera
09:34

Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera

Published on: January 27, 2023

  • Interproximal plaque collected via floss and total protein concentration measured using a fluorescence microplate assay.
  • Comparison of plaque levels between brushing alone versus brushing and flossing.

    • Main Results:

    • Both MTM and STM successfully distinguished between different plaque removal treatments.
    • Established fundamental profiles detailing mean changes in IPP protein concentration over time and by treatment.
    • Protein concentration demonstrated a strong correlation with direct plaque weight measurements, validating its use.

    Conclusions:

    • The developed MTM and STM provide objective and quantitative assessments of IPP.
    • Total protein concentration serves as a reliable biomarker for quantifying IPP levels.
    • These models offer a sensitive tool for clinical research in oral hygiene and plaque control.