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Taming chronic cough.

Matthew A Rank1, Pramod Kelkar, John J Oppenheimer

  • 1Division of Allergic Diseases, Mayo Clinic, Rochester, Minnesota, USA.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|April 27, 2007
PubMed
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This review highlights evidence-based strategies for diagnosing and treating chronic cough. Focusing on common causes like asthma and reflux significantly improves cough resolution in adults.

Area of Science:

  • Pulmonology
  • Allergy and Immunology

Background:

  • Chronic cough is a common condition with various underlying causes.
  • Effective diagnosis and treatment strategies are crucial for patient management.

Purpose of the Study:

  • To review existing evidence for a systematic approach to chronic cough diagnosis and treatment.
  • To provide an evidence-based framework for clinicians.

Main Methods:

  • Comprehensive literature search of MEDLINE, PubMed, EMBASE, and CINAHL.
  • Inclusion of studies relevant to chronic cough diagnosis and treatment, including non-randomized and retrospective data.
  • Keywords included common causes such as asthma, gastroesophageal reflux, and upper airway cough syndrome.

Main Results:

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  • Limited randomized controlled trials exist for chronic cough.
  • Prospective noncontrolled trials show high resolution rates by addressing common causes: asthma, gastroesophageal reflux disease (GERD), and upper airway cough syndrome (UACS).
  • Pediatric studies suggest differentiating wet vs. dry cough and investigating specific symptoms for underlying conditions.

Conclusions:

  • Allergists are well-positioned to manage chronic cough due to their expertise in upper and lower airway disorders.
  • An evidence-based, systematic approach focusing on common etiologies is effective for chronic cough management.