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Updated: Jul 15, 2026
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Protracted Aspergillus versicolor endophthalmitis caused by corneal microperforation
Y-D Bifrare1, T J Wolfensberger
1Hopital Ophtalmique Jules Gonin, Lausanne, Switzerland.
Klinische Monatsblatter Fur Augenheilkunde
|April 27, 2007
Summary
A corneal microperforation led to a prolonged Aspergillus versicolor endophthalmitis. Prompt diagnosis and treatment, including vitrectomy and antifungal therapy, improved visual acuity in this rare fungal eye infection case.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Describes a rare case of endophthalmitis caused by Aspergillus versicolor.
- Highlights the link between corneal microperforation and fungal eye infections.
Observation:
- A 58-year-old patient presented with decreased vision and severe intraocular inflammation six months after eye trauma from an old cable.
- Examination revealed a corneal scar, anterior segment inflammation, and a significant chorioretinal infiltrate.
Findings:
- Bacteriological analysis identified Aspergillus versicolor as the causative agent.
- Vitrectomy with antifungal medication (Amikacin, Vancomycin, Amphotericin B) and subsequent topical steroids and oral antifungals led to improved vision.
Implications:
- Corneal microperforations are a potential risk factor for protracted Aspergillus endophthalmitis.
- Aspergillus versicolor, often found in environmental sources like insulation and cables, should be considered in fungal endophthalmitis diagnoses.
- Early recognition and aggressive treatment are crucial for managing this severe ocular infection.
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