Related Experiment Video
Updated: Jul 15, 2026
10:43
Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells
Published on: March 5, 2019
[Multipotential differentiation and potential applications of adipose-derived stem cells]
Zheng-Bin Han1, Hong-Xing Chen, Ji-Xian Deng
1Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China. hanzhengbin@yahoo.com.cn
Summary
Adipose-derived stem cells (ADSCs) are multipotent cells from fat tissue. This review explores ADSC plasticity and their potential in tissue engineering, organ repair, and gene therapy.
Area of Science:
- Stem cell biology
- Regenerative medicine
Context:
- Adipose tissue is an abundant source of multipotent stem cells.
- Adipose-derived stem cells (ADSCs) share properties with mesenchymal stem cells.
- ADSCs offer a readily accessible cell source with minimal harvesting morbidity.
Purpose:
- To review the plasticity of adipose-derived stem cells (ADSCs).
- To highlight recent advances in ADSC research.
- To discuss the challenges and future prospects for ADSC applications.
Summary:
- ADSCs exhibit multipotency, differentiating into various cell lineages including adipogenic, osteogenic, chondrogenic, myogenic, endothelial, hematopoietic, hepatic, islet, and neurogenic cells.
- The abundance and accessibility of adipose tissue make ADSCs promising for tissue engineering, organ repair, and gene therapy.
- This review consolidates current knowledge on ADSC plasticity and applications.
Impact:
- Advances understanding of stem cell differentiation potential.
- Identifies therapeutic applications for ADSCs in regenerative medicine.
- Provides insights into overcoming challenges for clinical translation of ADSC-based therapies.
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