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A generative bias towards average complexity in artificial cell lineages.

Rolf Lohaus1, Nicholas L Geard, Janet Wiles

  • 1Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204-5001, USA.

Proceedings. Biological Sciences
|May 3, 2007
PubMed
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Generative bias alone does not explain evolutionary increases in phenotypic complexity. A computational model suggests selective biases play a critical role in driving and maintaining complexity.

Area of Science:

  • Evolutionary biology
  • Developmental biology
  • Computational modeling

Background:

  • Life's evolution shows a trend toward increased phenotypic complexity.
  • Natural selection is a proposed driver, but generative bias is an alternative hypothesis.

Purpose of the Study:

  • To computationally model a developmental system and test if generative bias drives increased phenotypic complexity.
  • To analyze mutational effects on complexity in generated organisms.

Main Methods:

  • Developed a computational model of a developmental system.
  • Generated random organisms with varying phenotypic complexity.
  • Analyzed distributions of mutational effects on complexity.

Main Results:

Related Experiment Videos

  • Highly complex organisms are generatable, but complexity measures have trade-offs.
  • Generative bias favors higher complexity only in the simplest phenotypes.
  • Generative bias favors lower complexity in highly complex phenotypes.

Conclusions:

  • Generative biases alone are insufficient to explain long-term evolutionary increases in phenotypic complexity.
  • A generative bias towards average complexity suggests selective biases are crucial for driving and maintaining complexity.