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Updated: Jul 15, 2026

Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
Three-dimensional computerized anthropometry of the nose: landmark representation compared to surface analysis.
Virgilio F Ferrario1, Fabrizio Mian, Redento Peretta
1University of Milan, Milan, Italy.
Nasal measurements from plaster casts closely match direct subject measurements for distances and angles. For accurate nasal volume and surface area, a surface-based approach is recommended over landmark-based methods.
Area of Science:
- Anthropometry
- 3D facial imaging
- Craniofacial research
Background:
- Accurate three-dimensional (3D) nasal measurements are crucial for various applications, including surgical planning and anthropometric analysis.
- Traditional methods involve direct measurements or analysis of physical models, while newer techniques utilize digital surface reconstruction.
Purpose of the Study:
- To compare the accuracy of 3D nasal measurements obtained from direct digitization of subjects versus plaster casts.
- To evaluate nasal dimensions derived from a surface-based approach against those from a landmark-based representation.
Main Methods:
- Direct digitization of soft-tissue nasal landmarks on 20 healthy adults.
- Mathematical reconstruction of digitized stone nasal casts using nonuniform rational B-splines (NURBS) curves.
- Computation of linear distances, angles, volumes, and surface areas using both landmark and surface-based (NURBS) methods.
Main Results:
- Measurements from plaster casts were slightly smaller than direct subject measurements (differences: -0.05 to -1.58 mm).
- The surface-based approach yielded significantly larger values for volume (3.5x) and surface area (2.1x) compared to the landmark-based method.
- Strong correlations were found between the two methods for volume (r=0.881) and surface area (r=0.924), with good estimation capabilities.
Conclusions:
- Nasal distances and angles measured on plaster casts are comparable to direct digital measurements for practical purposes.
- The surface-based approach provides more accurate results for nasal volume and surface area.
- Landmark-based data can be used to estimate surface area and volume, though with less precision.
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