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Updated: Jul 15, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Xenograft calcification in Reiter's syndrome
J Harrison Howard1, Silvio H Litovsky, Jose A Tallaj
1Departments of Surgery, Birmingham Veterans Administration Medical Center, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA.
Abstract:
Reiter's syndrome is characterized by multiple joint arthropathy, and can affect the heart. One manifestation of cardiac involvement is aortic insufficiency that may require valve replacement. Herein is reported a case with rapidly progressive and severe calcification of a bovine pericardial prosthesis seven years after implantation, in the setting of Reiter's syndrome. Based on this experience, it is suggested that echocardiographic evaluations be scheduled more frequently than usual if a bioprosthetic rather than mechanical valve is chosen for a patient with Reiter's syndrome.
