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Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
[Electroconvulsive therapy in treatment of depression]
1Rigshospitalet, Psykiatrisk Klinik, København Ø. tom.g.bolwig@rh.hosp.dk
Abstract:
ECT is the most powerful treatment of severe melancholic/ psychotic depression. A treatment series consists of 8-12 sessions, given 3 times a week under anaesthesia, muscle relaxation and artificial ventilation with 100% oxygen. EEG, EMG, EKG and pulse oximetry are monitored. Benzodiazepines, anticonvulsants and lithium salts should be avoided during treatment with ECT. Ambulatory single ECT sessions with an interval of 3-4 weeks (maintenance-ECT) is recommended in drug-resistant depression. In Denmark, 5% of all patients admitted to psychiatric departments were treated with ECT; 18% of patients diagnosed with depression were given ECT. ECT is a safe and sometimes life-saving treatment.
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