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Updated: Jul 14, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
Published on: January 21, 2011
Fast computation of many-particle hydrodynamic and electrostatic interactions in a confined geometry
Juan P Hernández-Ortiz1, Juan J de Pablo, Michael D Graham
1Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706-1691, USA.
Abstract:
An O(N) method is presented for calculation of hydrodynamic or electrostatic interactions between N point particles in a confined geometry. This approach splits point forces or sources into a local contribution for which rapidly decaying free-space analytical solutions to the Stokes or Poisson equations are used, and a global contribution whose effect is determined numerically using a fast iterative method. The scheme is applied to Brownian dynamics simulations of flowing confined polymer solutions, and the effects of concentration on hydrodynamically induced migration phenomena are illustrated.
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