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Updated: Jul 14, 2026
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
Published on: February 9, 2020
[The correlation between ultrastructure of lymphatic capillary and neck lymph node metastasis laryngeal carcinoma]
1Department of Otorhinolaryngology, the Second Hospital of Jilin University, Changchun, China.
Objective:
To study the correlation between ultrastructure of lymphatic capillary in pericancerous tissue and neck lymph node metastasis in laryngeal carcinoma.
Method:
Transmission electronic microscope was applied to observe and compare ultrastructure of lymphatic capillary in 8 normal laryngeal epithelial tissue and 12 pericancerous tissue of laryngeal cancer.
Result:
Lymphatic capillary of pericancerous tissue was significantly dilated compared with normal laryngeal tissue. A large amount of endothelial cell junction was open and devoid of basement membrane. Some endothelial cells of lymphatic capillary were destroyed or broken completely.
Conclusion:
Ultrastructure of lymphatic capillary in pericancerous tissue is an important factor of laryngeal cancer metastasis through lymphatic system. This research offers theoretic basis for laryngeal carcinoma metastasis mechanism and prevention.
