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Updated: Jul 14, 2026

Defining Substrate Specificities for Lipase and Phospholipase Candidates
Published on: November 23, 2016
Enzymes phosphorylating lipids and polysaccharides
1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Abstract:
Phosphorylation plays an important role in regulation of living functions of organisms; phosphorylation may significantly alter chemical properties of proteins, lipids, and carbohydrates. Canonical kinases catalyze transfer of terminal phosphate group from ATP (or other NTPs) to specific nucleophilic groups of proteins, lipids, and polysaccharides. Recently, unique kinases, catalytically active antibodies (abzymes) phosphorylating proteins, lipids, and polysaccharides have also been discovered. This review highlights biological functions and enzymatic characteristics of canonical kinases and abzymes phosphorylating lipids and polysaccharides.
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