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Young onset Hemifacial Spasm in patients with Chiari type I malformation
Andre Carvalho Felício1, Clecio de Godeiro, Vanderci Borges
1Movement Disorders Unit, Department of Neurology, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, Brazil. cf.andre@terra.com.br
Parkinsonism & Related Disorders
|May 25, 2007
Summary
Hemifacial spasm (HFS) linked to Chiari type I malformation (CIM) is uncommon. This study found HFS in 4.85% of CIM patients, noting early onset and potential BTX-A treatment effectiveness.
Area of Science:
- Neurology
- Neurosurgery
- Genetics
Background:
- Chiari type I malformation (CIM) is a rare cause of hemifacial spasm (HFS).
- Understanding the association between CIM and HFS is crucial for diagnosis and treatment.
- Peculiar phenotypic characteristics, such as a short neck, may be associated with CIM-related HFS.
Purpose of the Study:
- To evaluate the frequency of hemifacial spasm (HFS) in patients with Chiari type I malformation (CIM).
- To describe the clinical profile of HFS associated with CIM.
- To assess the efficacy of BTX-A injections as a treatment for HFS in CIM patients.
Main Methods:
- Retrospective evaluation of 103 subjects.
- Identification of patients with both CIM and HFS.
- Clinical data analysis and treatment outcome assessment for BTX-A injections.
Main Results:
- Hemifacial spasm (HFS) was found in 4.85% of the evaluated Chiari type I malformation (CIM) patients.
- HFS in CIM patients presented with young-onset facial spasms, differing from classical primary cases.
- Three patients treated with BTX-A injections showed favorable outcomes.
Conclusions:
- Hemifacial spasm (HFS) can be associated with Chiari type I malformation (CIM), particularly in young individuals with specific phenotypes like a short neck.
- BTX-A injections represent a viable alternative to posterior fossa decompression for HFS in selected CIM patients.
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