Related Experiment Video
Updated: Jul 14, 2026
06:43
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Ileal malignant melanoma causing intussusception: report of a case
Konstantinos Karmiris1, Maria Roussomoustakaki, Maria Tzardi
1Department of Gastroenterology, University Hospital, P.O. Box 1352, 71110, Heraklion, Crete, Greece.
Surgery Today
|May 25, 2007
Summary
This case study presents the first diagnosis of primary small intestine malignant melanoma (MM) using magnetic resonance enteroclysis (MRE). The rare ileal MM highlights the importance of considering unusual diagnoses in gastrointestinal oncology.
Area of Science:
- Gastrointestinal Oncology
- Medical Imaging
- Dermatopathology
Background:
- Cutaneous malignant melanoma (MM) commonly metastasizes to the gastrointestinal (GI) tract.
- Primary MM of the small intestine is considered a controversial and rare diagnosis in clinical practice.
Observation:
- A 76-year-old woman presented with an intraluminal tumor in the ileum.
- Radiological workup, including magnetic resonance enteroclysis (MRE), identified a large polypoid mass.
- Surgical excision and subsequent histological examination confirmed MM.
Findings:
- Postoperative examination did not reveal any primary cutaneous, anal, ocular, or other melanoma lesions.
- The patient developed brain metastasis and died 6 months after surgical resection.
- This represents the first reported case of primary small intestinal MM diagnosed using MRE.
Implications:
- Malignant melanoma can rarely originate in the small intestine, challenging existing diagnostic paradigms.
- Magnetic resonance enteroclysis (MRE) is a valuable tool for diagnosing rare small bowel tumors.
- This case underscores the need for thorough investigation in suspected cases of primary GI melanoma.
Related Concept Videos
01:29Intestinal Obstruction I: Introduction
Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
01:07Intestinal Obstruction II: Pathophysiology
Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
01:25Assessment of the Rectum and Anus
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
01:21Inflammatory Bowel Disease V: Surgical Management
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
01:19Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...