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Updated: Jul 14, 2026
07:02
Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
Acquired immunodeficiency syndrome related Kaposi's sarcoma eroding the maxillary bone
P A Konstantinopoulos1, H Goldsztein, B J Dezube
1Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
The Journal of Laryngology and Otology
|May 26, 2007
Summary
Kaposi's sarcoma (KS) commonly affects the mouth in AIDS patients. This case details hard palate KS invading maxillary bone, requiring a multidisciplinary approach for effective treatment.
Area of Science:
- Oncology
- Infectious Diseases
- Oral Surgery
Background:
- Oral Kaposi's sarcoma (KS) is a frequent complication of acquired immunodeficiency syndrome (AIDS).
- Approximately one-third of patients with AIDS-related KS experience oral lesions.
Observation:
- An unusual case of hard palate Kaposi's sarcoma is presented.
- The KS lesion demonstrated invasion into the underlying maxillary bone.
Findings:
- The patient underwent excisional biopsy for diagnosis and treatment.
- Management involved localized radiation and systemic chemotherapy with liposomal doxorubicin.
Implications:
- This case underscores the importance of a multidisciplinary approach for managing complex maxillofacial KS.
- Involvement of Ear, Nose, and Throat (ENT), oncology, and infectious disease specialists is crucial for optimal patient care.
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