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Sonographic features of liver involvement by lymphoma
Javier F Castroagudín1, Esther Molina, Ihab Abdulkader
1Departments of Gastroenterology and Hepatology, University Hospital of Santiago, Santiago de Compostela, Spain. javier.fernandez.castroagudin@sergas.es
Summary
Ultrasound can help diagnose liver infiltration by lymphoma. Key signs include multiple liver nodules, enlarged spleen, and lymph nodes, but biopsy is needed for confirmation.
Area of Science:
- Radiology
- Oncology
- Hepatology
Background:
- The liver is a common extranodal site for lymphoma.
- Lymphoma accounts for a small percentage of focal liver lesions.
- Limited research exists on sonographic patterns of liver lymphoma.
Purpose of the Study:
- To describe sonographic features of lymphoma with liver involvement.
- To evaluate the diagnostic accuracy of sonography for liver lymphoma.
Main Methods:
- Retrospective review of abdominal sonography in 23 patients with confirmed lymphoma and liver involvement.
Main Results:
- Hepatomegaly and splenomegaly were most common.
- Liver nodules appeared as multiple small lesions in 50% of patients.
- No sonographic pattern differences were noted between high- and low-grade non-Hodgkin lymphoma.
Conclusions:
- Sonography can aid in diagnosing liver lymphoma.
- Consider lymphoma with liver involvement if multiple focal lesions, splenomegaly, and lymphadenopathy are present.
- Histologic confirmation is essential due to low specificity.
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