Related Experiment Video
Updated: Jul 14, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Actual antimicrobial chemotherapy prescription in infant and child]
A Bourrillon1, G Benoist, R Cohen
1Service de pédiatrie générale, hôpital Robert-Debré, 48, boulevard Sérurier, 75935 Paris cedex 19, France. antoine.bourrillon@rdb.aphp.fr
Abstract:
Antimicrobial chemotherapy prescription should take into account the following items: 1) accurate diagnosis (most often clinical) and definition criteria of infectious diseases; 2) treatment justification; 3) confirmation of a bacterial etiology (now facilitated in some clinical situations by broadly available easy-to-use rapid diagnosis tests); 4 evidence-based antimicrobial choices; 5) modalities of prescriptions guided by official authorities (guidelines from French agency of medicinal products).
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Antimicrobial Effectiveness
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Antiprotozoal Agents