Related Experiment Video
Updated: Jul 14, 2026

10:14
Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Hypotony maculopathy.
Vital Paulino Costa1, Enyr Saran Arcieri
1Glaucoma Service, Department of Ophthalmology, University of Campinas, São Paulo, Brazil. vp.costa@uol.com.br
Acta Ophthalmologica Scandinavica
|June 5, 2007
Summary
Hypotony maculopathy, a condition causing vision loss after eye surgery or injury, involves inward scleral collapse and retinal folds. Prompt treatment to elevate intraocular pressure (IOP) is crucial for visual recovery.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Glaucoma Surgery Complications
Background:
- Hypotony maculopathy, described by Dellaporta in 1954, typically follows antiglaucoma surgery or eye injuries.
- Characterized by hypotony and fundus abnormalities like papilledema, vascular tortuosity, and chorioretinal folds.
- Scleral collapse leads to choroidal and retinal redundancy, causing wrinkling and radial retinal folds around the fovea.
Purpose of the Study:
- To review the definition, underlying mechanisms, clinical presentation, and treatment strategies for hypotony maculopathy.
- To highlight the importance of timely diagnosis and intervention for hypotony maculopathy.
- To discuss factors associated with the development of hypotony maculopathy.
Main Methods:
- Literature review of hypotony maculopathy.
- Analysis of clinical findings and pathological mechanisms.
- Summary of current treatment approaches for hypotony maculopathy.
Main Results:
- Hypotony maculopathy occurs in up to 20% of glaucoma filtering surgeries, potentially increasing with antimetabolite use.
- Associated factors include young age, myopia, primary surgery, systemic conditions, and elevated preoperative intraocular pressure (IOP).
- Treatment aims to elevate IOP, reverse scleral bowing, and improve visual acuity.
Conclusions:
- Successful treatment hinges on accurate cause identification and prompt intervention to prevent permanent macular damage.
- Delayed normalization of IOP can lead to irreversible chorioretinal changes and vision impairment.
- Understanding the pathophysiology is key to managing hypotony maculopathy effectively.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
