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Updated: Jul 14, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
The relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration
Ehud Rechtman1, Alon Harris, Brent Siesky
1Goldschleger Eye Institute, Tel-Hashomer, Israel.
Background And Objective:
To evaluate the relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration.
Patients And Methods:
Thirteen patients with age-related macular degeneration were assessed by both color Doppler imaging and scanning laser ophthalmoscope indocyanine green (ICG) angiography. Color Doppler imaging was used to measure peak systolic and end diastolic velocity (from which the resistance index, a measure of the resistance to flow downstream, was calculated) in the retrobulbar vessels. Scanning laser ophthalmoscope ICG angiograms were analyzed by area dilution analysis for quantitative choroidal fluorescence intensity assessment. Color Doppler imaging parameters were correlated with scanning laser ophthalmoscope ICG area dilution analysis parameters.
Results:
A good correlation was found between the posterior ciliary arteries resistance index and scanning laser ophthalmoscope ICG area dilution analysis fluorescence duration.
Conclusions:
Scanning laser ophthalmoscope ICG area dilution analysis "duration" may serve as an alternative to color Doppler imaging in assessing the resistance to blood flow in the posterior ciliary arteries.
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