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Updated: Jul 14, 2026
13:19
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
[Screening for prostate cancer--what does the evidence show?]
1Arhus Universitetshospital, Skejby. borre@dadlnet.dk
Ugeskrift for Laeger
|June 8, 2007
Summary
Prostate cancer screening using PSA tests lacks sufficient evidence for routine use. Current data cannot confirm if screening reduces prostate cancer deaths, so Denmark
Area of Science:
- Urology
- Preventive Medicine
- Evidence-Based Medicine
Context:
- Prostate cancer screening is a debated topic in public health.
- The use of Prostate-Specific Antigen (PSA) testing is a primary method for screening.
- Cochrane reviews provide a critical assessment of existing medical evidence.
Purpose:
- To discuss the findings of a recent Cochrane review on prostate cancer screening.
- To evaluate the evidence regarding the effectiveness of different screening strategies (mass, selective, opportunistic) in reducing prostate cancer mortality.
- To inform policy decisions regarding PSA-based screening.
Summary:
- A recent Cochrane review found insufficient evidence to support or refute routine prostate cancer screening.
- The review compared mass, selective, and opportunistic screening against no screening.
- Current evidence does not demonstrate a reduction in prostate cancer mortality from screening.
Impact:
- The findings support maintaining the Danish policy of not recommending PSA-based screening.
- Ongoing large randomized screening trials are crucial for future evidence generation.
- Policy decisions should await mature results from these trials to potentially alter recommendations.
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