Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Rotavirus vaccines: recent developments and future considerations.

Juana Angel1, Manuel A Franco, Harry B Greenberg

  • 1Instituto de Genética Humana, Pontificia Universidad Javeriana, Carrera 7, 40-62, Bogotá, Colombia. jangel@javeriana.edu.co

Nature Reviews. Microbiology
|June 16, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rotavirus-specific intestinal resident memory T cells induced by oral vaccination in early-life mice may contribute to protective immunity.

Journal of leukocyte biology·2026
Same author

Human vaccine responses regulated by parallel cytokine pathways.

Nature immunology·2026
Same author

Nur77 Is Associated With Polyfunctional Properties in Virus-Specific Human CD8<sup>+</sup> T Cells.

European journal of immunology·2026
Same author

Virus-like Particles and Spectral Flow Cytometry for Identification of Dengue Virus-Specific B Cells in Mice and Humans.

Viruses·2026
Same author

Prolonged Fever in Pediatric Dengue is Associated With Clinical Severity and Immune Dysregulation.

The Pediatric infectious disease journal·2026
Same author

Development of intestinal tissue-resident T cells in early-life mice before and after weaning.

Scientific reports·2025
Same journal

Waterborne diseases and climate change.

Nature reviews. Microbiology·2026
Same journal

Climate adaptation and biodiversity shape West Nile virus risk in cities.

Nature reviews. Microbiology·2026
Same journal

Climate factors and evolution drive cholera surges in Dhaka.

Nature reviews. Microbiology·2026
Same journal

Climate change boosts Salmonella antimicrobial resistance.

Nature reviews. Microbiology·2026
Same journal

Reframing risk assessment for malaria elimination in a changing climate.

Nature reviews. Microbiology·2026
Same journal

Bacterial vesicles protect the membrane during polymyxin stress.

Nature reviews. Microbiology·2026
See all related articles

Two new rotavirus vaccines are safe and effective for children. Further research on rotavirus, immune responses, and vaccine efficacy will guide future vaccine improvements and development.

Area of Science:

  • Virology
  • Immunology
  • Vaccinology

Background:

  • Rotavirus gastroenteritis is a significant cause of severe illness in young children globally.
  • Two novel rotavirus vaccines are currently available worldwide.
  • Continuous improvement and development of rotavirus vaccines are necessary.

Purpose of the Study:

  • To review recent advancements in rotavirus knowledge.
  • To discuss the host immune response to rotavirus infection.
  • To evaluate the efficacy and safety of current rotavirus vaccines.

Main Methods:

  • Literature review of recent scientific publications.
  • Analysis of data on rotavirus epidemiology and pathogenesis.
  • Synthesis of information on vaccine efficacy and safety trials.

Related Experiment Videos

Main Results:

  • Current rotavirus vaccines demonstrate good safety and efficacy profiles.
  • Understanding of rotavirus strains and host immunity is evolving.
  • Identified areas for potential vaccine enhancement.

Conclusions:

  • Recent scientific insights support the improvement of existing rotavirus vaccines.
  • Knowledge gained will inform the development of next-generation rotavirus vaccines.
  • Ongoing research is crucial for combating rotavirus gastroenteritis.