Related Experiment Video
Updated: Jul 14, 2026

Operation Procedure and Precautions of Lingnan Fire-Needle Therapy in Osteoporosis Model Rats
Published on: April 26, 2024
[Nonpharmacological treatment of osteoporosis]
1Klinika za reumatske bolesti i rehabilitaciju, Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb.
Abstract:
Exercise and prevention of falls are the cornerstone of nonpharmacological treatment of osteoporosis (OP). Mechanical stress has osteogenic properties. Proprioceptive training can improve balance. Intermittent mechanical stimuli are most appropriate type of functional bone adaptation. Recommendations for exercises include type (aerobic, weight-bearing, resistance), frequency (minimum 3x weekly), duration (minimum 20-30 minutes) and intensity of 50-80% of repetitive maximum (RM). Target muscle groups for intervention are spine extensors and hip muscles. Eliminaton of risk of falls and proprioceptive exercises can reduce incidency of falls and related fractures.
Related Concept Videos
Osteoclasts in Bone Remodeling
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Remodeling
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...