Related Experiment Video
Updated: Apr 27, 2026

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research
Published on: March 1, 2024
Abstract:
Tendons are made of connective tissue and passively transfer force from muscle contraction to the bone and are daily exposed to mechanical loading. They are built of tenocytes inserted in the extracellular matrix in which collagen type I fibers maintain its strength. Stretching the collagen fibers of more than 10% of the original length can cause them to crack. In the development of chronic degenerative tendinopathy there is overlapping of reactive acute tendinopathy, tendon dysrepair (failed healing) and degenerative tendinopathy. Acute condition requires unloading in the first few days and in the chronic phase, it is recommended to exercise even over the limit of pain. The role of clinician is to distinguish reversible from irreversible condition and utilize the remaining reparations potential or to consider surgical treatment methods.
Related Concept Videos
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Alterations in Muscle Tone ll
Skeletal Muscle Anatomy
Alterations in Muscle Tone lll
Somatic Spinal Reflexes
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Long-term Potentiation
Hebbian LTP
LTP can occur when...

