Related Experiment Video
Updated: Jul 14, 2026
10:10
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
Pulmonary tuberculosis in diabetic patients
L Pandya1, N Al-Sharif, A Maraey
1Sahary Chest Hospital, and King Khalid University Hospital, Riyadh, Saudi Arabia.
Annals of Saudi Medicine
|May 1, 1991
Summary
This study found that 8.7% of pulmonary tuberculosis patients had diabetes mellitus, with a higher prevalence in Saudi patients. Diabetic patients showed no difference in sputum conversion rates compared to non-diabetic patients.
Area of Science:
- Medicine
- Public Health
- Infectious Diseases
Background:
- Diabetes mellitus is a growing global health concern.
- Pulmonary tuberculosis remains a significant infectious disease worldwide.
- Comorbidities like diabetes can impact tuberculosis treatment outcomes.
Purpose of the Study:
- To determine the prevalence of diabetes mellitus in patients with pulmonary tuberculosis.
- To investigate the association between diabetes and tuberculosis characteristics, including treatment response.
Main Methods:
- Retrospective analysis of 1566 pulmonary tuberculosis cases.
- Data collection on patient demographics, comorbidities (diabetes mellitus), treatment regimens, and sputum conversion.
- Statistical comparison of outcomes between diabetic and non-diabetic patients.
Main Results:
- A prevalence of 8.7% for diabetes mellitus was observed among tuberculosis patients.
- Saudi patients exhibited a significantly higher prevalence of diabetes (13%) compared to non-Saudis (5%).
- Sputum conversion rates were similar between diabetic and non-diabetic patients, with no statistically significant difference.
Conclusions:
- Diabetes mellitus is a common comorbidity in pulmonary tuberculosis patients, particularly in the Saudi population.
- The presence of diabetes did not adversely affect sputum conversion rates with standard first-line antitubercular drugs.
- Further research may explore long-term outcomes and specific management strategies for this patient group.
Related Concept Videos
01:29Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:28Pulmonary Tuberculosis V
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
01:26Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:31Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
01:17Other Pulmonary Disorders
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.