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Updated: Jul 14, 2026

07:49
Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
[Anaphylaxis after carrying out prick tests].
S Vázquez-Cortés1, T Robledo Echarren, B Bartolomé
1Servicio de Alegia, Hospital Clínico Universitario San Carlos, Madrid. cmcocera@meditex.es
Summary
Skin prick testing (SPT) can rarely cause severe allergic reactions like anaphylaxis. This case highlights the risk of anaphylaxis after SPT with cat dander extract, emphasizing the need for preparedness.
Area of Science:
- Allergology
- Immunology
- Dermatology
Background:
- Skin prick testing (SPT) is a standard diagnostic tool in allergology.
- While generally safe, rare systemic reactions, including anaphylaxis, have been reported.
- Cat dander allergy is common, often presenting with respiratory and ocular symptoms.
Observation:
- A 23-year-old female with a history of asthma and rhinoconjunctivitis experienced anaphylaxis post-SPT.
- The reaction occurred 20 minutes after SPT using a cat dander extract.
- Symptoms included severe ocular irritation, dysphonia, and a sensation of pharyngeal occupation.
Findings:
- The patient developed anaphylaxis with hemodynamic compromise following SPT.
- Cat dander extract was identified as the trigger for the severe systemic reaction.
- This case underscores the potential for serious adverse events during SPT.
Implications:
- SPT should be conducted by trained specialists in facilities equipped to manage anaphylaxis.
- Awareness of potential systemic reactions is crucial for patient safety during allergy testing.
- Prompt recognition and management are vital for patients experiencing anaphylaxis after SPT.
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