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Updated: Jul 14, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

[Peritoneal mesothelioma: an inusual clinical presentation in a patient without exposure to asbestos]

J Ponce Lorenzo1, A Giménez Ortiz, F Aparisi Aparisi

  • 1Servicio de Oncología Médica, Hospital Universitario La Fe, Valencia. joseponcelorenzo@hotmail.com

Anales De Medicina Interna (Madrid, Spain : 1984)
|June 26, 2007
PubMed

Insights

This case report details a rare peritoneal malignant mesothelioma in a 64-year-old man. Despite palliative chemotherapy, the patient succumbed to treatment toxicity, highlighting challenges in managing this rare cancer.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Malignant mesothelioma is a rare cancer originating from mesothelial surfaces.
  • Asbestos exposure is the primary known cause of malignant mesothelioma.

Observation:

  • A 64-year-old man presented with constitutional syndrome and right pleural effusion.
  • He had no history of asbestos inhalation exposure.
  • Positron emission tomography combined with computed tomography (PET/TC) aided diagnosis and staging.

Findings:

  • The patient was diagnosed with primary malignant mesothelioma of the peritoneum.
  • Treatment with cisplatin-pemetrexed chemotherapy showed partial response after three cycles.
  • The patient's outcome was fatal due to secondary chemotherapy toxicity.

Implications:

  • This case underscores the possibility of malignant mesothelioma developing without asbestos exposure.
  • It highlights the diagnostic utility of PET/TC in peritoneal mesothelioma.
  • The case emphasizes the critical risks of chemotherapy toxicity in palliative cancer care.

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