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[The methods of establishing rhinogenic model of acute sinusitis in the rabbit]
1wangpju@sohu.com
Objective:
To create a rhinogenic model of acute sinusitis in the rabbits.
Method:
Thirty-two New Zealand white rabbits were divided into four groups: A group (nasal cavity-implanted with synthetic sponge), B group (nasal cavity-implanted with synthetic sponge and bacteria inoculation), C group (bacteria inoculation group), D group (control). The animals were examined by the methods of endoscope, histology and bacteriology after two weeks.
Result:
The success rate of model were 60% (A group), 100% (B group) and 0% (C,D group). Both maxillary sinus and ethmoid sinus had developed inflammation.
Conclusion:
A rhinogenic model of acute sinusitis can be created by inserting synthetic sponge instilled with pathogenic bacteria into nasal cavity. This is a simple method and has the potential to be valuable to study on FESS.
