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Arterial oxygen saturation, blood pressure, and pulse rate during upper gastrointestinal endoscopy--influence of
Y Kinoshita1, S Ishido, K Nishiyama
1Department of Medicine, Miki City Hospital, Hyogo-ken, Japan.
Abstract:
We studied the effect of sedation by I.V. meperidine on blood pressure, pulse rate, and arterial oxygen saturation during upper gastrointestinal endoscopy. Meperidine increased the tolerance of the patients and attenuated the endoscopy-induced rise in blood pressure and pulse rate. Arterial oxygen saturation was transiently depressed in the first few minutes of the endoscopic procedure even without sedation, and meperidine administration did not aggravate this oxygen desaturation. Therefore, meperidine may be a favorable sedative for upper gastrointestinal endoscopy because its treatment increases the tolerance of patients and decreases cardiac oxygen demand without decreasing arterial oxygen saturation.
Insights
Intravenous meperidine sedation improves patient tolerance and reduces cardiovascular stress during upper gastrointestinal endoscopy. This sedative effectively manages blood pressure and pulse rate without worsening oxygen saturation.
Area of Science:
- Gastroenterology
- Pharmacology
- Anesthesiology
Background:
- Upper gastrointestinal endoscopy requires sedation for patient comfort and tolerance.
- Sedation can impact vital signs, including blood pressure, pulse rate, and oxygen saturation.
Purpose of the Study:
- To evaluate the effects of intravenous meperidine sedation on hemodynamic parameters and oxygen saturation during upper gastrointestinal endoscopy.
Main Methods:
- Patients undergoing upper gastrointestinal endoscopy received intravenous meperidine for sedation.
- Blood pressure, pulse rate, and arterial oxygen saturation were monitored throughout the procedure.
Main Results:
- Meperidine enhanced patient tolerance to the endoscopic procedure.
- It attenuated the expected rise in blood pressure and pulse rate.
- Arterial oxygen saturation showed a transient dip early in the procedure, unaffected by meperidine.
Conclusions:
- Intravenous meperidine is a favorable sedative for upper gastrointestinal endoscopy.
- It improves patient tolerance and reduces cardiac oxygen demand without compromising arterial oxygen saturation.