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Updated: Jul 13, 2026
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Salmonella pseudomembranous colitis
Andrew Beck1, Candice McNeil, George Abdelsayed
1Northwestern University, USA.
Connecticut Medicine
|July 11, 2007
Abstract:
Pseudomembranous colitis is most often associated with antibiotic use and caused most often by Clostridium difficile. Aclinical syndrome and pathology that is identical can be caused rarely by other organisms. We report a case of Salmonella enterica pseudomembranous colitis and briefly review the literature regarding rare causes of this syndrome.
Insights
Pseudomembranous colitis, typically from antibiotics and Clostridium difficile, can rarely be caused by other pathogens. This case highlights Salmonella enterica as a rare cause of this condition.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Microbiology
Background:
- Pseudomembranous colitis is predominantly linked to antibiotic-induced disruption of gut microbiota.
- Clostridium difficile is the most frequent causative agent identified in antibiotic-associated colitis.
Observation:
- This report details a rare clinical presentation of pseudomembranous colitis.
- The observed case involved infection with Salmonella enterica, an unusual pathogen for this condition.
Findings:
- The study identifies Salmonella enterica as a rare cause of pseudomembranous colitis.
- The clinical syndrome and pathological findings were identical to typical Clostridium difficile infections.
Implications:
- This finding expands the differential diagnosis for pseudomembranous colitis beyond Clostridium difficile.
- Clinicians should consider non-C. difficile pathogens in pseudomembranous colitis, especially in specific epidemiological contexts.
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