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Capsule endoscopy in paediatrics: multicentric Belgian study
Daniel Urbain1, Micheline Tresinie, Danny De Looz
1Hepato-gastroenterology Unit, AZ VUB, Brussels. daniel.urbain@az.vub.ac.be
Insights
Capsule endoscopy (CE) is a valuable tool for diagnosing pediatric small bowel diseases, particularly for obscure gastrointestinal bleeding and iron deficiency anemia. CE provided significant diagnostic insights in children with recurrent abdominal pain, impacting treatment decisions.
Area of Science:
- Pediatric Gastroenterology
- Medical Imaging
- Diagnostic Endoscopy
Background:
- Capsule endoscopy (CE) is a minimally invasive diagnostic tool for small bowel evaluation.
- Data on CE utilization in pediatric populations is limited.
- This study reviews Belgian pediatric CE cases to assess its utility.
Purpose of the Study:
- To evaluate the effectiveness of capsule endoscopy in diagnosing pediatric small bowel diseases.
- To analyze indications, findings, and clinical impact of CE in children.
- To determine CE's role in managing pediatric gastrointestinal conditions.
Main Methods:
- A retrospective review of capsule endoscopy procedures in pediatric patients (< or = 18 years) across seven Belgian academic hospitals.
- Data collected included indications for CE, prior diagnostic procedures, final diagnoses, and the clinical impact of CE findings.
- The study period was from November 2002 to December 2005.
Main Results:
- Seventeen children underwent CE, with primary indications being obscure gastrointestinal bleeding/iron deficiency anemia (10 cases) and chronic/recurrent abdominal pain (7 cases).
- Lesions detected included ulcerations, jejunal varices, intussusception, and active bleeding; 7 cases had normal findings.
- CE yielded relevant diagnostic findings in 60% of OGIB/IDA cases and 43% of abdominal pain cases, influencing therapy in 44% of patients.
Conclusions:
- Capsule endoscopy is a useful diagnostic tool for pediatric patients with obscure gastrointestinal bleeding/iron deficiency anemia.
- CE can also be beneficial for selected pediatric cases of recurrent abdominal pain.
- Further prospective, controlled trials comparing CE with emerging techniques like CT enterography are necessary.
Background And Study Aims:
Capsule Endoscopy (CE) is a noninvasive procedure for evaluating small bowel disease. Data concerning children are scarce. The aim of the present report was to review all paediatric cases investigated by CE in Belgium.
Patients And Methods:
The seven Belgian academic hospitals using the CE device (Given) were asked to collect information on CE performed in patients < or = 18 years. Main indications for performing VCE, former radiological and endoscopic procedures were collected, as well as final diagnosis and clinical impact of VCE findings.
Results:
From November 2002 until December 2005, VCE was performed in 17 children (mean age : 11.9 years, range : 5-18). Indications were occult gastro-intestinal bleeding (OGIB) and/or iron deficiency anaemia (IDA) (10 cases) and chronic and/or recurrent abdominal pain (7 cases). Mean duration of symptoms was 8.6 months. The mean number of endoscopic and radiological procedures before performing CE was 4.2 per patient. Detected lesions were ulcerations (6 cases), jejunal varices (1), ileo-ileal invagination (2), active bleeding (1), and normal findings (7). In the indication of OGIB/IDA, relevant findings having an impact on the diagnosis were found in 60% of the cases. In the group with chronic and recurrent abdominal pain, CE brought relevant findings in 43%. CE findings had an impact on therapy in 44% of the patients.
Conclusions:
CE could be a useful tool for clinical work-up of difficult paediatric cases, not only in the indication of IDA/OGIB, but also for selected cases of recurrent abdominal pain, but prospective controlled trials including emerging techniques like CT enterography are mandatory.
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