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Updated: Jul 13, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
[Invasive Streptococcus agalactiae infections in non-pregnant adults]
N Lefebvre1, E Forestier, M Mohseni-Zadeh
1Service des maladies infectieuses et tropicales, centre hospitalier universitaire de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France. n.lefebvre@yahoo.fr
Medecine Et Maladies Infectieuses
|July 17, 2007
Summary
Invasive Streptococcus agalactiae (Group B Streptococcus) infections disproportionately affect adults with underlying conditions like diabetes. These infections often manifest as urinary tract, skin, or bone infections, highlighting the need for awareness in at-risk populations.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Medicine
Context:
- Streptococcus agalactiae (Group B Streptococcus) is a significant pathogen in non-pregnant adults.
- Invasive infections are more prevalent in the elderly and individuals with comorbidities.
Purpose:
- To describe the underlying conditions and clinical characteristics of adult patients with invasive Streptococcus agalactiae infections.
- To analyze the epidemiology and clinical presentation of these infections in a hospital setting.
Summary:
- A retrospective review of 64 patients with invasive S. agalactiae infections (1997-2006) revealed a mean age of 59 years.
- 90.6% of patients had at least one underlying condition, most commonly diabetes mellitus (43.7%), peripheral vascular disease (34.4%), and malignancies (20.3%).
- Common presentations included urinary tract infections (32.8%), skin/soft-tissue infections (25%), and osteoarthritis (21.9%), with bacteremia in 31.2%.
Impact:
- This study underscores the critical role of underlying diseases in the pathogenesis of S. agalactiae infections in adults.
- Findings emphasize the need for increased clinical vigilance for S. agalactiae in non-pregnant adults, especially those with chronic health conditions.
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