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Updated: Jul 13, 2026

Whole-Kidney Three-Dimensional Staining with CUBIC
Published on: July 18, 2022
[Kikuchi-Fujimoto's disease: 3 cases report]
M Khalifa1, N Kaabia, N Gannouchi
1CHU Farhat Hached, Service de Médecine Interne et Maladies Infectieuses, 4000 Sousse Tunisie. fethi.bahri@famso.rnu.tn
Objective:
Kikuchi-Fujimoto's is a rare disease, characterized by the diversity of clinical symptoms, with predominance of enlarged cervical lymph nodes and fever. We report three cases with different presentations.
Material And Method:
The first one was a classic form, frequently described in literature. The second was characterized by concomitant association with systemic lupus erythematosus. Histologic findings of Kikuchi's disease were the presence of nuclear debris, absence of haemathoxilin bodies and neutrophils polynuclears. The presentation of the third case was acute meningitis with cervical lymphadenopathy. Lumber puncture showed lymphocytic meningitis, mild hypoglycorrhachia and hyperproteinrrhachia. Favourable evolution was noted in all cases without recurrence.
Conclusion:
Wathever its presentation the prognosis of the Kikuchi-Fujimoto's disease is generally benign with a spontaneously favorable evolution between 1 to 6 months.
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