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Updated: Jul 13, 2026
17:13
Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
Published on: April 28, 2013
Revascularization for post-transplant renal artery stenosis
Kai Ming Chow1, Cheuk Chun Szeto, Paul Sing Fun Lee
1Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong. chow_kai_ming@alumni.cuhk.net
Nephrology (Carlton, Vic.)
|July 20, 2007
Summary
Percutaneous transluminal angioplasty significantly improves hypertension in transplant renal artery stenosis patients. However, this intervention shows minimal impact on enhancing overall renal function.
Area of Science:
- Nephrology
- Cardiovascular Surgery
- Interventional Radiology
Background:
- Transplant renal artery stenosis (TRAS) is a complication impacting graft survival.
- Percutaneous transluminal angioplasty (PTA) is increasingly adopted for TRAS management.
Purpose of the Study:
- To evaluate the efficacy of PTA as a primary intervention for transplant renal artery stenosis.
- To assess the impact of PTA on blood pressure and renal function in TRAS patients.
Main Methods:
- A single-center study involving 18 consecutive patients with angiographically confirmed TRAS.
- Patients underwent PTA as the primary treatment modality.
- Follow-up included assessment of blood pressure and estimated glomerular filtration rate (eGFR).
Main Results:
- Significant reductions in mean arterial pressure (P < 0.001), systolic blood pressure (P = 0.002), and diastolic blood pressure (P = 0.002) were observed.
- Mean arterial pressure decreased from 105.9 to 98.6 mmHg.
- No significant improvement in eGFR was noted at 6 months post-intervention (P = 0.82).
Conclusions:
- PTA demonstrates a significant beneficial effect on managing hypertension associated with TRAS.
- The impact of PTA on improving renal function in TRAS patients appears limited.
- PTA is a viable option for blood pressure control in TRAS.
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