Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid function abnormalities in HIV-infected patients.

Christopher J Hoffmann1, Todd T Brown

  • 1Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|July 20, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phone-based screening versus home-based screening after tuberculosis in India (TB Aftermath): a multicentre, open-label, randomised, controlled, non-inferiority trial.

The Lancet. Global health·2026
Same author

Multidimensional Poverty and Implementation Reach of Household Contact Tracing for Tuberculosis in South Africa: Analysis of a Randomized Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Dental disease among adults with and without HIV in the MACS/WIHS Combined Cohort Study (MWCCS).

BMC oral health·2026
Same author

Qualitative Identification of HIV Care Engagement Challenges and Preferences for Differentiated Care Service Delivery Models Post-Incarceration in South Africa.

Inquiry : a journal of medical care organization, provision and financing·2026
Same author

5' leader defects drive persistent HIV-1 viremia on long-term ART.

Nature communications·2026
Same author

Clinic and Provider Innovations to Improve Tuberculosis Infection Screening and Preventive Therapy Uptake in Brazil: Qualitative Findings From the PREVINE-TB Study.

Journal of the International Association of Providers of AIDS Care·2026
Same journal

Reconsidering ambiguous language in infectious disease consult recommendations.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Antibiotic Treatment Duration for Uncomplicated Monomicrobial Enterococcal Bloodstream Infection: A Multicenter Target Trial Emulation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Anticalcitonin: Limited utility of a context-dependent biomarker demonstrated in another real-world data set.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Procalcitonin Testing in Community-Acquired Pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Wanted: A Relevant Correlate of Protection for Dengue Vaccines.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

Abnormal thyroid function tests are common in human immunodeficiency virus (HIV)-infected patients, with specific patterns like subclinical hypothyroidism and low thyroxine levels increasing during treatment. Routine screening for asymptomatic individuals is not recommended.

Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Clinical Chemistry

Background:

  • Abnormal thyroid function tests are frequent in human immunodeficiency virus (HIV)-infected individuals.
  • Overt thyroid disease prevalence is similar to the general population, but specific abnormal patterns are more common.
  • Nonthyroidal illness (euthyroid sick syndrome) is prevalent in advanced acquired immunodeficiency syndrome.

Purpose of the Study:

  • To review current evidence on optimal laboratory evaluation of thyroid function in HIV-infected patients.
  • To highlight causes, presentation, and treatment of thyroid dysfunction in this population.
  • To discuss controversies surrounding thyroid screening in HIV-infected individuals.

Main Methods:

  • Literature review of current evidence on thyroid function testing and dysfunction in HIV-infected patients.

Related Experiment Videos

  • Summary of findings on specific thyroid conditions like subclinical hypothyroidism, isolated low free thyroxine, and Graves disease.
  • Discussion of diagnostic approaches and screening recommendations.

    • Main Results:

    • Subclinical hypothyroidism (elevated thyroid-stimulating hormone) and isolated low free thyroxine levels are more prevalent during antiretroviral therapy.
    • Graves disease can occur during immune reconstitution.
    • Thyroid function testing in symptomatic patients should start with thyroid-stimulating hormone measurement.

    Conclusions:

    • There is insufficient evidence to recommend routine thyroid screening for asymptomatic HIV-infected individuals.
    • Optimal laboratory evaluation and management of thyroid dysfunction in HIV-infected patients require careful consideration of specific clinical contexts.
    • Further research may clarify screening guidelines and optimal diagnostic strategies.