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Three new cytotoxic Diels-Alder-type adducts from Morus australis

Qing-Jian Zhang1, Yan-Bo Tang, Ruo-Yun Chen

  • 1The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, PR China.

Chemistry & Biodiversity
|July 20, 2007
PubMed

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[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

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Cycloaddition Reactions: Overview

Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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