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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

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Published on: February 13, 2021

Surgery for heart failure: now something for everyone?

Stephen Westaby1

  • 1Oxford Heart Centre, John Radcliffe Hospital, Headington, Oxford, UK. stephen.westaby@orh.nhs.uk <stephen.westaby@orh.nhs.uk>

Heart Failure Clinics
|July 24, 2007
PubMed

Insights

Surgical options for heart failure are advancing beyond transplants. Left ventricular restoration and new blood pump technologies offer hope for many patients with advanced heart disease.

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Regenerative Medicine

Background:

  • Cardiac surgery has evolved significantly over 50 years.
  • Medical treatments and cardiac resynchronization therapy have limitations for heart failure patients.
  • Donor heart availability is insufficient for the majority of heart failure cases.

Purpose of the Study:

  • To explore emerging surgical strategies for heart failure.
  • To highlight the potential of left ventricular restoration surgery.
  • To discuss the role of bioengineered blood pumps in future therapies.

Main Methods:

  • Review of current trends in cardiac surgery.
  • Analysis of the relationship between cardiac structure and function.
  • Examination of advancements in blood pump technology.

Main Results:

  • Non-transplant surgical options are expanding for heart failure.
  • Left ventricular restoration surgery leverages cardiac mechanics for improved function.
  • Bioengineered blood pumps represent a promising alternative and platform for novel therapies.

Conclusions:

  • Surgical interventions beyond transplantation are crucial for managing heart failure.
  • Left ventricular restoration offers a potential solution based on cardiac geometry.
  • Blood pump bioengineering paves the way for innovative genetic and stem cell therapies for heart failure.

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