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Rare-event analysis in flow cytometry

Albert D Donnenberg1, Vera S Donnenberg

  • 1University of Pittsburgh School of Medicine, Hillman Cancer Research Center Suite2.42c, 5117 Center Avenue, Pittsburgh, PA 15213-2582, USA. donnenbergad@upmc.edu

Clinics in Laboratory Medicine
|July 31, 2007
PubMed

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...