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Effects of once weekly rosuvastatin among patients with a prior statin intolerance
James M Backes1, Patrick M Moriarty, Janelle F Ruisinger
1Department of Pharmacy Practice, Kansas University Medical Center, Kansas City, Kansas, USA.
Abstract:
Statins possess an excellent safety profile and are generally well tolerated when administered in the standard once-daily dosing regimen. A small percentage of patients however, discontinue therapy because of adverse events such as myalgias. The investigators describe 8 patients with previous intolerance to daily statin dosing and examine their responses to once-weekly rosuvastatin therapy. In conclusion, once-weekly rosuvastatin may be a feasible and effective option for patients previously intolerant to once-daily statin dosing.
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