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Published on: December 2, 2016

Cardiac troponin I release after hip surgery correlates with poor long-term cardiac outcome

S Ausset1, Y Auroy, E Lambert

  • 1Hôpital d'Instruction des Armées Percy, Service d'Anesthésie-Réanimation, Clamart Cedex, France. sylvain.ausset@gmail.com

European Journal of Anaesthesiology
|August 2, 2007
PubMed

Insights

Perioperative myocardial damage, indicated by troponin I release after hip surgery, is common and significantly increases the risk of major cardiac events and mortality within one year.

Area of Science:

  • Cardiology
  • Orthopedic Surgery
  • Biomarkers

Background:

  • Perioperative myocardial damage is a concern following hip surgery.
  • Troponin I is a key biomarker for detecting cardiac injury.

Purpose of the Study:

  • To determine the incidence of perioperative myocardial damage after hip surgery using troponin I.
  • To investigate the association between troponin I elevation and long-term cardiovascular outcomes.

Main Methods:

  • Serial troponin I measurements were performed on 88 patients undergoing hip surgery over three postoperative days.
  • Elevated troponin I levels were defined as values above the 99th percentile (0.08 ng mL(-1)).
  • Major cardiac events and all-cause mortality were tracked during hospitalization and for one year post-surgery.

Main Results:

  • Troponin I levels were elevated in 12.5% of patients, with most remaining asymptomatic.
  • Patients with elevated troponin I had a significantly higher incidence of major cardiac events (45% vs. 4%) and all-cause mortality (36% vs. 7%) at one year.
  • Troponin I elevation and age were independent predictors of cardiac events and mortality.

Conclusions:

  • Troponin I release is a frequent occurrence after hip surgery.
  • Elevated troponin I levels post-hip surgery are strongly associated with adverse long-term cardiovascular outcomes and increased mortality.
Abstract

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