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Updated: Jul 13, 2026
10:24
Cytosolic Calcium Measurements in Renal Epithelial Cells by Flow Cytometry
Published on: October 28, 2014
[Impaired calcium homeostasis, clinical impact]
1Medizinische Universitätskinderklinik Bern. marco.janner@bluewin.ch
Therapeutische Umschau. Revue Therapeutique
|August 10, 2007
Summary
Calcium homeostasis abnormalities are rare in childhood but present with diverse symptoms, necessitating consideration in differential diagnoses. This review covers calcium regulation and when to measure plasma calcium levels.
Area of Science:
- Pediatric Endocrinology
- Biochemistry
- Mineral Metabolism
Context:
- Calcium homeostasis is crucial for health, involving complex interactions between the skeleton, gut, and kidneys.
- Abnormalities in calcium regulation can manifest with varied and sometimes subtle clinical signs in children.
- Despite rarity, calcium imbalances must be considered in pediatric differential diagnoses.
Purpose:
- To review the physiological factors regulating calcium homeostasis and bone formation.
- To outline clinical scenarios warranting plasma calcium level measurement in pediatric practice.
Summary:
- This review details the physiological mechanisms controlling calcium balance and bone health.
- It emphasizes the heterogeneous and changing clinical presentations of calcium homeostasis disorders in children.
- Guidance is provided on when to assess plasma calcium levels in pediatric patients.
Impact:
- Enhances understanding of pediatric calcium regulation.
- Aids clinicians in diagnosing and managing calcium-related disorders in children.
- Improves recognition of calcium homeostasis abnormalities in pediatric differential diagnoses.
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