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Published on: September 27, 2018
Sacral nerve stimulation for fecal disorders: evolution, current status, and future directions
1Chirurgische Klinik der Universität Erlangen, Erlangen, Germany. Klaus.Matzel@chir.imed.uni-erlangen.de
Sacral nerve stimulation (SNS) improves fecal incontinence and quality of life by stimulating the anorectal continence organ. This therapy is effective across various causes, with a predictive test guiding permanent implantation.
Area of Science:
- Neuroscience
- Gastroenterology
- Urology
Background:
- Sacral nerve stimulation (SNS) has been used since 1994 to treat fecal incontinence.
- Its application has expanded, becoming a valuable therapeutic option.
- Patient selection evolved from conceptual to pragmatic trial-and-error, with a predictive temporary test phase.
Purpose of the Study:
- To evaluate the effectiveness of sacral nerve stimulation for fecal incontinence.
- To assess the impact of SNS on patients' quality of life.
- To explore the mechanism of action and potential new applications of SNS.
Main Methods:
- Temporary test stimulation to predict clinical benefit.
- Implantation of a neurostimulation device for chronic stimulation.
- Clinical trials (single and multicentre) across diverse etiologies.
Main Results:
- Permanent SNS improves or restores continence.
- SNS significantly enhances patients' quality of life.
- Effectiveness is demonstrated across a wide range of fecal incontinence causes.
Conclusions:
- Sacral nerve stimulation is an effective treatment for fecal incontinence.
- The therapy offers substantial improvements in quality of life.
- Further research is needed to fully understand its mechanism and expand applications.
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