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In vivo confocal microscopy in different types of posterior polymorphous dystrophy
1Prabha Eye Clinic and Research Center, Bangalore and Vittala Institute of Ophthalmology, Bangalore, India. kb_7375@yahoo.co.in
Indian Journal of Ophthalmology
|August 19, 2007
Summary
Posterior polymorphous dystrophy (PPMD) is a rare corneal condition. Confocal microscopy revealed distinct morphologic features across its three main types, aiding diagnosis.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Microscopy
Background:
- Posterior polymorphous dystrophy (PPMD) is an inherited bilateral corneal disease.
- It is characterized by abnormal changes in Descemet's membrane and corneal endothelium.
- PPMD is often asymptomatic and diagnosed incidentally.
Observation:
- This case series details the in vivo morphologic characteristics of PPMD.
- Confocal microscopy was utilized to examine corneal tissues.
- The study focused on differentiating the three recognized types of PPMD.
Findings:
- Confocal microscopy demonstrated unique microstructural patterns for each of the three PPMD types.
- Specific features observed included guttae, edema, and stromal opacity.
- These findings highlight the utility of confocal microscopy in classifying PPMD subtypes.
Implications:
- Accurate classification of PPMD subtypes can guide clinical management.
- Confocal microscopy offers a non-invasive method for detailed corneal assessment.
- Understanding PPMD morphology aids in differentiating it from other corneal dystrophies.
