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Updated: Jul 13, 2026

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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Decision-making about PSA testing and prostate biopsies: a qualitative study embedded in a primary care randomised
Kerry N L Avery1, Jane M Blazeby, J Athene Lane
1Department of Social Medicine, University of Bristol, Bristol, United Kingdom. kerry.avery@bristol.ac.uk <kerry.avery@bristol.ac.uk>
European Urology
|August 22, 2007
Summary
Men generally found prostate-specific antigen (PSA) testing and biopsy acceptable. However, accurate risk perception is crucial for informed decision-making regarding prostate cancer screening.
Area of Science:
- Urology
- Oncology
- Health Psychology
Background:
- Prostate cancer screening involves prostate-specific antigen (PSA) testing and often biopsy.
- Understanding men's decision-making processes regarding these procedures is vital for effective patient care.
Purpose of the Study:
- To explore men's decision-making experiences concerning PSA testing and prostate biopsy.
- To identify factors influencing acceptance and refusal of these diagnostic procedures.
Main Methods:
- Qualitative interview study nested within the Prostate Testing for Cancer and Treatment (ProtecT) trial.
- Interviews conducted with 58 men aged 50-69 years who either accepted or refused PSA testing and/or prostate biopsy.
Main Results:
- Most men viewed PSA testing and biopsy as acceptable, irrespective of outcomes.
- Perceptions of low risk for prostate cancer were common among men who responded to or ignored PSA testing invitations, and those who refused biopsy.
- Anxiety about biopsy and misunderstandings regarding urinary symptoms and prostate cancer risk were identified.
Conclusions:
- While PSA testing and biopsy are generally accepted, men's risk perceptions may not always align with reality.
- Tailored information provision is recommended to enhance informed decision-making in prostate cancer screening.
