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Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Periodontal care may improve systemic inflammation.
Arnon Blum1, Eran Front, Aviva Peleg
1Department of Internal Medicine A, Baruch-Padeh Poriya Medical Center, Lower Galilee, Israel. navablum@hotmail.com
Periodontitis, an oral infection, is linked to general inflammation and cardiovascular disease risk. Treating gum disease effectively reduced inflammation markers, suggesting a potential preventive strategy for heart conditions.
Area of Science:
- Oral Health
- Cardiovascular Health
- Inflammation Research
Background:
- Periodontitis is a chronic infectious disease affecting tooth-supporting structures, causing systemic inflammation.
- This inflammation is potentially linked to cardiovascular disease (CVD) markers like high-sensitivity C-reactive protein (hs-CRP).
- The study investigated if treating periodontitis could reduce inflammation and mitigate future CVD risk.
Purpose of the Study:
- To determine the association between periodontitis and hs-CRP, a marker for general inflammation and CVD.
- To evaluate if managing periodontal disease improves inflammatory markers.
- To explore the potential of periodontal treatment as a preventive measure for cardiovascular disease.
Main Methods:
- A prospective case-controlled pilot study involving 9 patients with severe periodontitis and 9 healthy controls.
- Patients received conservative periodontal treatment without surgery.
- Periodontal status and hs-CRP levels were assessed at baseline and after 3 months of treatment.
Main Results:
- Periodontal treatment significantly improved clinical parameters: reduced probing depth, improved clinical attachment level, decreased bleeding on probing, and lower plaque index.
- Pre-treatment hs-CRP levels in periodontitis patients (2.97 mg/L) were significantly higher than in healthy controls (0.25 mg/L).
- After 3 months of treatment, hs-CRP levels in patients decreased significantly (from 2.97 to 2.3 mg/L).
Conclusions:
- Periodontitis is an infectious condition associated with chronic inflammation and may be a risk factor for cardiovascular disease.
- Effective treatment of periodontitis leads to a reduction in systemic inflammation markers.
- Periodontal disease management may serve as a crucial preventive strategy for cardiovascular disease.
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