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Updated: Jul 12, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
[Uterine malformations and reproduction]
1Service de gynécologie-obstétrique, pôle Femme-et-Enfant, CHU Jean-Verdier, APHP, avenue du 14-Juillet, 93143 Bondy, France. christophe.poncelet@jvr.aphp.fr
Abstract:
The frequency of uterine malformations impacting on reproduction seems not easy to determine. Their diagnosis needs specific explorations (hysterosalpingography, hysteroscopy and laparoscopy). Spontaneous fertility may be impaired in relation with uterine abnormalities. All these abnormalities could have repercussions on the conceptus' evolution like abortion, preterm delivery, vascular pathologies and intrauterine growth restriction. Ovarian function does not seem to be altered even though implantation rate could be reduced. Surgery, especially endoscopy, allows a precise diagnosis, a prognostic evaluation and an adequate treatment improving conception rates and pregnancy outcome. Mainly hysteroscopic septum section and expansion metroplasty were regularly described.
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